The Anti-Müllerian hormone, also known as the Müllerian-inhibiting hormone (AMH), is found in both women and men. Its purpose in women is to guide the growth of the ovarian follicle, and in male foetuses to guide the development of the male reproductive parts. AMH is produced in the gonad cells in men and in the ovarian follicles in women. Men’s AMH concentration first increases after birth and then decreases again after puberty.
Women, on the other hand, have low AMH concentrations at birth and in childhood, but they begin to increase, reaching a peak in early adulthood. The number of follicles decreases with the woman’s age, and therefore also AMH concentration decreases. The hormone is no longer detected after menopause.
Because women’s Anti-Müllerian hormone is produced in the ovarian follicles, it is used as an indicator of the functioning of the ovaries and the remaining ovarian follicle reserve in women.
The result is ready approximately in 5 business days.
When should AMH be measured?
AMH tests are done when:
- Wanting to investigate fertility
- Planning fertility treatment
- Suspecting ovarian cancer
- Performing sex assignment, when it is not obvious at birth whether a child is a girl or a boy
- Investigating sexual and puberty development disorders
What does an AMH test measure?
AMH concentration indicates the number of ovarian follicles. The ovarian follicles produce AMH, so AMH concentration also decreases when their number decreases. Some women may still have ovarian follicles left, even if the functioning of the ovaries has prematurely declined.
Some ovarian cancers produce AMH, and the test can show how the cancer treatment is working, or in the case of a suspected relapse, whether the cancer has relapsed.
How to interpret the AMH test result?
- 15–18 yrs: 0.29 – 11.77 µg/l
- 19–24 yrs: 1.22 – 11.70 µg/l
- 25–29 yrs: 0.89 – 9.85 µg/l
- 30–34 yrs: 0.58 – 8.13 µg/l
- 35–39 yrs: 0.15 – 7.49 µg/l
- 40–44 yrs: 0.03 – 5.47 µg/l
- 45–50 yrs: 0.01 – 2.71 µg/l
- ≥ 51 yrs: no reference values available
- 15–18 yrs: 2.35 – 18.2 µg/l
- ≥ 19 yrs: 0.77 – 14.5 µg/l
Please contact your physician or other healthcare professional if you suspect an illness or need help interpreting the results.
Read more about defining reference values.
What can cause elevated AMH values?
In women who have received fertility treatment and in whom high AMH concentrations are measured, the treatment can be found to work and activate the ovaries.
What can cause decreased AMH values?
In a woman, low AMH concentrations suggest that the number of ovarian follicles has decreased (no more ovarian follicles are produced after birth).
The most typical additional AMH tests:
- Follicle stimulating hormone has effects on the growth and maturation of eggs (1422 S-FSH)
- Luteinising hormone regulates gametes and sex hormones (2265 S-LH)
SYNLAB test list: Anti-Müllerian hormone (AMH) https://www2.synlab.fi/laboratoriokasikirja/tutkimuskuvaukset/anti-muller-hormoni-seerumista-9475-s-amh/
Terveyskirjasto health library: Naisen lapsettomuus https://www.terveyskirjasto.fi/terveyskirjasto/tk.koti?p_artikkeli=dlk00737&p_hakusana=amh
LabTests online: Anti-Mullerian hormone https://labtestsonline.org.uk/tests/anti-mullerian-hormone
Fasting is not required
This examination does not require fasting